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Massachusetts to Buffalo trains

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Trip Overview

The train between Massachusetts and Buffalo takes 26h 40m. The train runs, on average, 6 times per week from Massachusetts to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 40m
Duration
496 mi
Distance
$347
Average price
6 times a week
Frequency

Massachusetts to Buffalo train times

Trains run 6 times a week between Massachusetts and Buffalo. The service departs Massachusetts at 12:50 PM in the afternoon, which arrives into Buffalo at 15:30:00. All services require a transfer, and take on average 26h 40m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Departing Tuesday, November 17, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Departing Wednesday, November 18, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Departing Thursday, November 19, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Departing Friday, November 20, 2026

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    Arrives next day

    AmtrakVIA Rail26h 40m • 1 change

Frequently asked questions

Want to know about travelling from Massachusetts to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Massachusetts to Buffalo.ExpandLaunch map view
  • Distance: 496.5 mi
  • Duration: 26h 40m

What companies run services between Massachusetts, USA and Buffalo, NY, USA?

Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $260–420 and the journey takes 11h 39m.

Operators