The average train between Marghera and Siena takes 4h 39m and the fastest train takes 3h 58m. There is a train service every few hours from Marghera to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Marghera and Siena. The earliest departure is at 5:38 AM in the morning, and the last departure from Marghera is at 7:38 PM which arrives into Siena at 7:55 AM. All services require a transfer, and take on average 4h 39m. The schedules shown below are for the next available departures.

4h 1m • 1 change

4h 38m • 1 change
Arrives next day

12h 17m • 1 change

4h • 1 change

4h 2m • 1 change

4h 2m • 1 change

3h 58m • 1 change

4h • 1 change

4h 2m • 1 change

4h 2m • 1 change

3h 58m • 1 change

4h • 1 change

4h 2m • 1 change

4h 2m • 1 change

3h 58m • 1 change
Want to know about travelling from Marghera to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Marghera to Siena. However, there are services departing from Marghera station and arriving at Siena station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 39m.
Marghera to Siena train services, operated by Trenitalia Frecce, depart from Venezia Mestre station.
Marghera to Siena train services, operated by Trenitalia Frecce, arrive at Siena station.
Book your Marghera to Siena train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Marghera and Siena is 250.2 km. The road distance is 336 km.
You can take a train from Venezia Mestre to Siena via Firenze S.M.N. in around 4h 21m.