The average train between Mannheim and Rome takes 13h 17m and the fastest train takes 10h 28m. The train service runs several times per day from Mannheim to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mannheim and Rome. The earliest departure is at 3:22 AM at night, and the last departure from Mannheim is at 11:00 PM which arrives into Rome at 1:24 PM. All services require a transfer at Basel SBB and take an average of 13h 17m. The schedules shown below are for the next available departures.



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10h 28m • 3 changesWant to know about travelling from Mannheim to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Rome. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Roma Termini station via Basel SBB station, Lugano station and Milano Centrale station. The journey, including transfers, takes approximately 13h 17m.
Mannheim to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Rome train services, operated by ItaloTreno, arrive at Roma Termini station.
Book your Mannheim to Rome train tickets online with Omio.
The distance between Mannheim and Rome is 899.7 km. The road distance is 1161 km.
You can take a train from Mannheim, Hauptbahnhof to Roma Termini via Basel SBB, Lugano, and Milano Centrale in around 11h 25m.