The average train between Mannheim and Pilsen takes 7h 52m and the fastest train takes 6h 44m. The train service runs several times per day from Mannheim to Pilsen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mannheim and Pilsen. The earliest departure is at 2:15 AM at night, and the last departure from Mannheim is at 9:29 PM which arrives into Pilsen at 8:47 AM. All services require a transfer at Frankfurt and take an average of 7h 52m. The schedules shown below are for the next available departures.



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6h 44m • 3 changesWant to know about travelling from Mannheim to Pilsen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Pilsen. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Plzen Hlavni Nadrazi station via Frankfurt station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 7h 52m.
Mannheim to Pilsen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Pilsen train services, operated by Die Länderbahn, arrive at Plzen Hlavni Nadrazi station.
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The distance between Mannheim and Pilsen is 354.9 km. The road distance is 419 km.
You can take a train from Mannheim, Hauptbahnhof to Plzen Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 7h 31m.