The average train between Manhattan and Framingham takes 5h 39m and the fastest train takes 4h 31m. The train service runs several times per day from Manhattan to Framingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Manhattan and Framingham. The earliest departure is at 5:44 AM in the morning, and the last departure from Manhattan is at 7:50 PM which arrives into Framingham at 5:30 AM. All services require a transfer at Boston and take an average of 5h 39m. The schedules shown below are for the next available departures.

4h 46m • 1 change

4h 31m • 1 change

4h 50m • 1 change

4h 45m • 1 change
Want to know about travelling from Manhattan to Framingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manhattan to Framingham. However, there are services departing from Manhattan station and arriving at Framingham station via Boston. The journey, including transfers, takes approximately 5h 39m.
Manhattan to Framingham train services, operated by Amtrak Northeast Regional, depart from Ny Moynihan Train Hall At Penn Station.
Manhattan to Framingham train services, operated by Amtrak Northeast Regional, arrive at Boston station.
The distance between Manhattan and Framingham is 269.6 km. The road distance is 403 km.
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 44m. Amtrak Northeast Regional also services this route every 3 hours.