The average train between Manchester and Kilmarnock takes 5h 18m and the fastest train takes 3h 36m. The train service runs several times per day from Manchester to Kilmarnock. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manchester and Kilmarnock. The earliest departure is at 4:54 AM at night, and the last departure from Manchester is at 8:21 PM which arrives into Kilmarnock at 7:51 AM. All services require a transfer, and take on average 5h 18m. The schedules shown below are for the next available departures.

5h • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 change
5h • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 change
4h 56m • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 change
5h 3m • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 change
5h • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 change
5h • 1 change
4h 30m • 1 change
3h 36m • 1 change
4h 36m • 1 changeWant to know about travelling from Manchester to Kilmarnock? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Kilmarnock. However, there are services departing from Manchester station and arriving at Kilmarnock station via Carlisle. The journey, including transfers, takes approximately 5h 18m.
Manchester to Kilmarnock train services, operated by TransPennine Express, depart from Manchester Piccadilly station.
Manchester to Kilmarnock train services, operated by TransPennine Express, arrive at Kilmarnock station.
Book your Manchester to Kilmarnock train tickets online with TransPennine Express and ScotRail.
The distance between Manchester and Kilmarnock is 278.1 km. The road distance is 340 km.
You can take a train from Manchester Piccadilly to Kilmarnock via Carlisle in around 4h 33m.