The average train between Manchester and Kilmarnock takes 5h 18m and the fastest train takes 3h 36m. The train service runs several times per day from Manchester to Kilmarnock. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manchester and Kilmarnock. The earliest departure is at 4:54 AM at night, and the last departure from Manchester is at 8:22 PM which arrives into Kilmarnock at 7:51 AM. All services require a transfer, and take on average 5h 18m. The schedules shown below are for the next available departures.

4h 36m • 1 change

4h 36m • 1 change

4h 21m • 1 change
Arrives next day

11h 29m • 1 change

5h • 1 change

4h 30m • 1 change

3h 36m • 1 change

4h 36m • 1 change

5h • 1 change

4h 30m • 1 change

3h 36m • 1 change

4h 36m • 1 change

5h • 1 change

4h 30m • 1 change

3h 36m • 1 change

4h 36m • 1 change

4h 56m • 1 change

4h 30m • 1 change

3h 37m • 1 change

4h 36m • 1 change

4h 28m • 1 change

4h 28m • 1 change
Arrives next day

13h 25m • 1 change

5h 3m • 1 change

4h 30m • 1 change

3h 36m • 1 change

4h 36m • 1 change
Want to know about travelling from Manchester to Kilmarnock? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Kilmarnock. However, there are services departing from Manchester station and arriving at Kilmarnock station via Carlisle. The journey, including transfers, takes approximately 5h 18m.
Manchester to Kilmarnock train services, operated by TransPennine Express, depart from Manchester Piccadilly station.
Manchester to Kilmarnock train services, operated by TransPennine Express, arrive at Kilmarnock station.
Book your Manchester to Kilmarnock train tickets online with TransPennine Express and ScotRail.
The distance between Manchester and Kilmarnock is 278.1 km. The road distance is 340 km.
You can take a train from Manchester Piccadilly to Kilmarnock via Carlisle in around 4h 42m.