The average train between Mainz and Siena takes 13h 18m and the fastest train takes 13h 11m. There is at least one train per day from Mainz to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Mainz and Siena. The earliest departure is at 7:04 AM in the morning, and the last departure from Mainz is at 7:29 AM which arrives into Siena at 8:40 PM. All services require a transfer at Frankfurt and take an average of 13h 18m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Siena. However, there are services departing from Mainz station and arriving at Siena station via Chiasso. The journey, including transfers, takes approximately 13h 18m.
Mainz to Siena train services, operated by vlexx, depart from Frankfurt station.
Mainz to Siena train services, operated by vlexx, arrive at Siena station.
Book your Mainz to Siena train tickets online with vlexx, Swiss Federal Railways (SBB CFF FFS) and 3 other operators.
The distance between Mainz and Siena is 776.8 km. The road distance is 1,100 km.
You can take a train from Mainz, Römisches Theater to Siena via Frankfurt, Chiasso, Milano Centrale, and Firenze S.M.N. in around 14h 47m.
