The average train between Mainz and Siegen takes 3h and the fastest train takes 2h 37m. There is a train service every few hours from Mainz to Siegen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Siegen. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 10:03 PM which arrives into Siegen at 1:00 AM. All services require a transfer at Frankfurt and take an average of 3h. The schedules shown below are for the next available departures.


2h 42m • 2 changes


2h 38m • 2 changes


3h 4m • 2 changes


2h 37m • 2 changes


2h 42m • 2 changes


2h 38m • 2 changes


3h 4m • 2 changes


2h 37m • 2 changes


2h 42m • 2 changes


2h 38m • 2 changes


3h 4m • 2 changes


2h 37m • 2 changes
Want to know about travelling from Mainz to Siegen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Siegen. However, there are services departing from Mainz station and arriving at Siegen station via Siegburg Bf. The journey, including transfers, takes approximately 3h.
Mainz to Siegen train services, operated by vlexx, depart from Frankfurt station.
Mainz to Siegen train services, operated by vlexx, arrive at Siegen Hbf station.
Book your Mainz to Siegen train tickets online with vlexx, Nederlandse Spoorwegen (NS) and 3 other operators.
The distance between Mainz and Siegen is 100.7 km. The road distance is 244 km.
You can take a train from Mainz, Römisches Theater to Siegen Hbf via Frankfurt and Siegburg Bf in around 3h 27m.