The average train between Mainz and Nyon takes 7h 30m and the fastest train takes 6h 52m. The train service runs several times per day from Mainz to Nyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mainz and Nyon. The earliest departure is at 1:42 AM at night, and the last departure from Mainz is at 11:12 PM which arrives into Nyon at 9:19 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 7h 30m. The schedules shown below are for the next available departures.



6h 52m • 3 changes



6h 52m • 3 changes



7h 55m • 3 changes



7h 36m • 3 changes



7h 37m • 3 changes



7h 52m • 3 changes



7h 52m • 3 changes



6h 52m • 3 changes



7h 34m • 3 changes



7h 52m • 3 changes



7h 52m • 3 changes



6h 52m • 3 changes



7h 34m • 3 changes



7h 52m • 3 changes



7h 52m • 3 changes



6h 52m • 3 changes



7h 34m • 3 changes



7h 52m • 3 changes



7h 52m • 3 changes



6h 52m • 3 changes



7h 37m • 3 changes



7h 52m • 3 changes



7h 52m • 3 changes



6h 52m • 3 changes
Want to know about travelling from Mainz to Nyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Nyon. However, there are services departing from Mainz station and arriving at Nyon station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 7h 30m.
Mainz to Nyon train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Nyon train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Renens VD station.
Book your Mainz to Nyon train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Nyon is 428 km. The road distance is 528 km.
You can take a train from Mainz, Römisches Theater to Nyon via Mannheim, Hauptbahnhof, Basel SBB, and Renens VD in around 7h 33m.