The average train between Mainz and Nijmegen takes 4h 3m and the fastest train takes 3h 33m. The train service runs several times per day from Mainz to Nijmegen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mainz and Nijmegen. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 7:14 PM which arrives into Nijmegen at 10:47 PM. All services require a transfer at Frankfurt and take an average of 4h 3m. The schedules shown below are for the next available departures.


3h 42m • 2 changes

3h 33m • 2 changes

3h 33m • 2 changes

3h 33m • 2 changes

5h 58m • 2 changes

3h 38m • 2 changes

3h 34m • 2 changes

3h 33m • 2 changes

5h 58m • 2 changes

3h 38m • 2 changes

3h 34m • 2 changes

3h 33m • 2 changes

5h 58m • 2 changes

3h 38m • 2 changes

3h 34m • 2 changes

3h 33m • 2 changes

5h 58m • 2 changes

3h 38m • 2 changes

3h 34m • 2 changes

3h 33m • 2 changesWant to know about travelling from Mainz to Nijmegen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Nijmegen. However, there are services departing from Mainz station and arriving at Nijmegen station via Arnhem Centraal. The journey, including transfers, takes approximately 4h 3m.
Mainz to Nijmegen train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Nijmegen train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Arnhem Centraal station.
Book your Mainz to Nijmegen train tickets online with Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) and 2 other operators.
The distance between Mainz and Nijmegen is 267.6 km. The road distance is 375 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Arnhem Centraal every 3 hours. Tickets cost €60–120 and the journey takes 2h 40m. Nederlandse Spoorwegen (NS) also services this route every 3 hours.