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Mainz to Nijmegen trains

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Trip Overview

The average train between Mainz and Nijmegen takes 3h 49m and the fastest train takes 3h 33m. The train service runs several times per day from Mainz to Nijmegen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 49m
Duration
375 km
Distance
€71
Average price
Twice daily
Frequency

Mainz to Nijmegen train times

Trains run twice daily between Mainz and Nijmegen. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 7:14 PM which arrives into Nijmegen at 10:47 PM. All services require a transfer at Frankfurt and take an average of 3h 49m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 33m • 2 changes
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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 33m • 2 changes
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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 33m • 2 changes
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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 33m • 2 changes
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Departing Monday, November 9, 2026

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    Deutsche Bahn Regio (DB Regional)Deutsche Bahn Intercity (DB IC)Nederlandse Spoorwegen (NS)5h 58m • 2 changes
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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 38m • 2 changes
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    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 34m • 2 changes
  •  → 

    vlexxNederlandse Spoorwegen (NS)Nederlandse Spoorwegen (NS)3h 33m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Mainz to Nijmegen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Nijmegen.ExpandLaunch map view
  • Distance: 374.9 km
  • Duration: 3h 49m

What companies run services between Mainz, Germany and Nijmegen, Netherlands?

Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Arnhem Centraal every 3 hours. Tickets cost €50–110 and the journey takes 2h 40m. Nederlandse Spoorwegen (NS) also services this route every 4 hours.

Operators