The average train between Mainz and Luthern takes 6h 17m and the fastest train takes 5h 5m. There is a train service every few hours from Mainz to Luthern. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mainz and Luthern. The earliest departure is at 1:42 AM at night, and the last departure from Mainz is at 11:12 PM which arrives into Luthern at 8:05 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 6h 17m. The schedules shown below are for the next available departures.


6h 25m • 2 changes


5h 40m • 2 changes


5h 41m • 2 changes


5h 41m • 2 changes


5h 5m • 2 changes


5h 38m • 2 changes


5h 38m • 2 changes


5h 39m • 2 changes


5h 5m • 2 changes


5h 38m • 2 changes


5h 38m • 2 changes


5h 39m • 2 changes


5h 5m • 2 changes


5h 38m • 2 changes


5h 38m • 2 changes


5h 39m • 2 changes
Want to know about travelling from Mainz to Luthern? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Luthern. However, there are services departing from Mainz station and arriving at Luthern station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 6h 17m.
Mainz to Luthern train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Luthern train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Luzern station.
Book your Mainz to Luthern train tickets online with Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) and 4 other operators.
The distance between Mainz and Luthern is 326.2 km. The road distance is 414 km.
You can take a train from Mainz, Römisches Theater to Luzern via Mannheim, Hauptbahnhof and Basel SBB in around 5h 44m.