The average train between Mainz and Itzehoe takes 6h 17m and the fastest train takes 5h 19m. There is a train service every few hours from Mainz to Itzehoe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Itzehoe. The earliest departure is at 3:34 AM at night, and the last departure from Mainz is at 10:35 PM which arrives into Itzehoe at 7:57 AM. All services require a transfer at Frankfurt and take an average of 6h 17m. The schedules shown below are for the next available departures.


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 22m • 2 changes


6h 23m • 2 changes


6h 23m • 2 changes


6h 23m • 2 changes


6h 23m • 2 changes
Want to know about travelling from Mainz to Itzehoe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Itzehoe. However, there are services departing from Mainz station and arriving at Itzehoe station via Hamburg Hbf. The journey, including transfers, takes approximately 6h 17m.
Mainz to Itzehoe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Itzehoe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Itzehoe station.
Book your Mainz to Itzehoe train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Itzehoe is 445.9 km. The road distance is 618 km.
You can take a train from Mainz, Römisches Theater to Itzehoe via Frankfurt and Hamburg Hbf in around 6h 7m.