The average train between Mainz and Eschwege takes 4h 13m and the fastest train takes 3h 42m. There is a train service every few hours from Mainz to Eschwege. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Eschwege. The earliest departure is at 3:34 AM at night, and the last departure from Mainz is at 7:34 PM which arrives into Eschwege at 11:51 PM. All services require a transfer at Frankfurt and take an average of 4h 13m. The schedules shown below are for the next available departures.


3h 47m • 2 changes

3h 42m • 2 changes

4h 17m • 2 changes

4h 17m • 2 changes

3h 47m • 2 changes

3h 42m • 2 changes

4h 17m • 2 changes

4h 17m • 2 changes

3h 47m • 2 changes

3h 42m • 2 changes

4h 17m • 2 changes

4h 17m • 2 changesWant to know about travelling from Mainz to Eschwege? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Eschwege. However, there are services departing from Mainz station and arriving at Eschwege station via Frankfurt. The journey, including transfers, takes approximately 4h 13m.
Mainz to Eschwege train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Eschwege train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Eschwege Stadtbahnhof station.
Book your Mainz to Eschwege train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Eschwege is 183 km. The road distance is 322 km.
You can take a train from Mainz, Römisches Theater to Eschwege Stadtbahnhof via Frankfurt and Göttingen in around 4h 5m.