The average train between Mainz and Brindisi takes 25h 39m and the fastest train takes 21h 10m. The train service runs several times per day from Mainz to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mainz and Brindisi. The earliest departure is at 1:14 PM in the afternoon, and the last departure from Mainz is at 9:14 PM which arrives into Brindisi at 6:24 PM. All services require a transfer at Frankfurt and take an average of 25h 39m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Brindisi. However, there are services departing from Frankfurt station and arriving at Brindisi Stazione Centrale station via Basel SBB station, Lugano station, Milano Centrale station and Mediopadana R.Emilia station. The journey, including transfers, takes approximately 25h 39m.
Mainz to Brindisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz to Brindisi train services, operated by Trenitalia Frecce, arrive at Brindisi Stazione Centrale station.
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The distance between Mainz and Brindisi is 1282.9 km. The road distance is 1653 km.
You can take a train from Mainz, Römisches Theater to Brindisi Stazione Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 19h 8m.