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Madrid to Palermo trains

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Trip Overview

The train between Madrid and Palermo takes 2d 22h. The train runs, on average, once a week from Madrid to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 22h
Duration
3,137 km
Distance
€490
Average price
Once a week
Frequency

Madrid to Palermo train times

Trains run once a week between Madrid and Palermo. The service departs Madrid at 8:30 PM in the evening, which arrives into Palermo at 19:04:00. All services require a transfer at Barcelona-Sants and take an average of 2d 22h. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

  •  → 

    Arrives +3 days

    Renfe AVERenfe ViajerosTrenitaliaTrenitalia FrecceTrenitalia Intercity2d 22h • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Palermo.ExpandLaunch map view
  • Distance: 3,137 km
  • Duration: 2d 22h

What companies run services between Madrid, Spain and Palermo, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Palermo Centrale via Barcelona-Sants, Lyon Part Dieu, Oulx-Cesana-Clav.-S., and Roma Termini in around 32h 33m.

Operators