The average train between Macclesfield and Slough takes 3h 4m and the fastest train takes 2h 37m. There is a train service every few hours from Macclesfield to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Macclesfield and Slough. The earliest departure is at 6:33 AM in the morning, and the last departure from Macclesfield is at 10:36 PM which arrives into Slough at 6:47 AM. All services require a transfer at London Euston and take an average of 3h 4m. The schedules shown below are for the next available departures.


2h 42m • 2 changes


2h 41m • 2 changes


2h 39m • 2 changes


2h 40m • 2 changes


2h 44m • 2 changes


2h 37m • 2 changes


2h 40m • 2 changes


2h 40m • 2 changes


3h 3m • 2 changes


3h 18m • 2 changes


3h 1m • 2 changes


2h 52m • 2 changes


2h 56m • 2 changes


2h 54m • 2 changes


2h 40m • 2 changes


2h 40m • 2 changes
Want to know about travelling from Macclesfield to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Macclesfield to Slough. However, there are services departing from Macclesfield station and arriving at Slough station via London Euston. The journey, including transfers, takes approximately 3h 4m.
Macclesfield to Slough train services, operated by Avanti West Coast, depart from Macclesfield station.
Macclesfield to Slough train services, operated by Avanti West Coast, arrive at Slough station.
Book your Macclesfield to Slough train tickets online with Avanti West Coast, London Underground (Tube) and Elizabeth Line (TfL).
The distance between Macclesfield and Slough is 220.6 km. The road distance is 300 km.
You can take a train from Macclesfield to Slough via London Euston, Euston station, Tottenham Court Road station, and Tottenham Court Rd in around 2h 42m.