The average train between Lytham St Annes and Slough takes 5h 3m and the fastest train takes 3h 48m. There is a train service every few hours from Lytham St Annes to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Lytham St Annes and Slough. The earliest departure is at 5:42 AM in the morning, and the last departure from Lytham St Annes is at 11:39 PM which arrives into Slough at 7:48 AM. All services require a transfer at Preston and take an average of 5h 3m. The schedules shown below are for the next available departures.



4h 18m • 3 changes



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4h 33m • 3 changes



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4h 18m • 3 changes
Want to know about travelling from Lytham St Annes to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lytham St Annes to Slough. However, there are services departing from Lytham St Annes station and arriving at Slough station via London Euston. The journey, including transfers, takes approximately 5h 3m.
Lytham St Annes to Slough train services, operated by Northern Trains Limited, depart from Preston station.
Lytham St Annes to Slough train services, operated by Northern Trains Limited, arrive at London Euston station.
Book your Lytham St Annes to Slough train tickets online with Northern Trains Limited, Avanti West Coast and 3 other operators.
The distance between Lytham St Annes and Slough is 296.5 km. The road distance is 393 km.
Avanti West Coast operates a train from Preston to London Euston hourly. Tickets cost £75–130 and the journey takes 2h 13m. Caledonian Sleeper also services this route twice daily.