The average train between Lyon and Mendrisio takes 6h 35m and the fastest train takes 6h 10m. The train service runs several times per day from Lyon to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Lyon and Mendrisio. The earliest departure is at 8:32 AM in the morning, and the last departure from Lyon is at 5:23 PM which arrives into Mendrisio at 11:42 PM. All services require a transfer, and take on average 6h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Lyon to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Mendrisio. However, there are services departing from Lyon station and arriving at Mendrisio station via Milano Centrale. The journey, including transfers, takes approximately 6h 35m.
Lyon to Mendrisio train services, operated by Trenitalia, depart from Lyon Part Dieu station.
Lyon to Mendrisio train services, operated by Trenitalia, arrive at Mendrisio station.
Book your Lyon to Mendrisio train tickets online with Trenitalia and Swiss Federal Railways (SBB CFF FFS).
The distance between Lyon and Mendrisio is 321.2 km. The road distance is 503 km.
You can take a train from Lyon Part Dieu to Mendrisio via Milano Centrale in around 6h 18m.
