The average train between Lyon and La Réole takes 10h and the fastest train takes 6h 59m. The train service runs several times per day from Lyon to La Réole. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Lyon and La Réole. The earliest departure is at 6:40 AM in the morning, and the last departure from Lyon is at 6:10 PM which arrives into La Réole at 8:46 AM. All services require a transfer at Toulouse Matabiau and take an average of 10h. The schedules shown below are for the next available departures.


8h 4m • 2 changes

7h 40m • 2 changesArrives next day


14h 36m • 2 changes

8h 4m • 2 changes

7h 40m • 2 changesArrives next day


15h 35m • 2 changes

6h 59m • 2 changes

8h 31m • 2 changesArrives next day


17h 30m • 2 changes

6h 59m • 2 changes

7h 28m • 2 changesArrives next day


14h 36m • 2 changesWant to know about travelling from Lyon to La Réole? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to La Réole. However, there are services departing from Lyon station and arriving at La Réole station via Toulouse Matabiau. The journey, including transfers, takes approximately 10h.
Lyon to La Réole train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to La Réole train services, operated by TGV inOui, arrive at La Reole station.
Book your Lyon to La Réole train tickets online with TGV inOui and Société Nationale des Chemins de fer Français (SNCF).
The distance between Lyon and La Réole is 404 km. The road distance is 757 km.
You can take a train from Lyon Part Dieu to La Reole via Toulouse Matabiau and Agen in around 7h 29m.