The average train between Lyon and Istres takes 5h 13m and the fastest train takes 2h 54m. The train service runs several times per day from Lyon to Istres. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lyon and Istres. The earliest departure is at 6:28 AM in the morning, and the last departure from Lyon is at 10:06 PM which arrives into Istres at 8:49 AM. All services require a transfer at Marseille St Charles and take an average of 5h 13m. The schedules shown below are for the next available departures.


4h 21m • 2 changes


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3h 43m • 2 changes


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3h 10m • 2 changes


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Want to know about travelling from Lyon to Istres? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Istres. However, there are services departing from Lyon station and arriving at Istres station via Marseille St Charles. The journey, including transfers, takes approximately 5h 13m.
Lyon to Istres train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Lyon Part Dieu station.
Lyon to Istres train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Miramas station.
Book your Lyon to Istres train tickets online with Société Nationale des Chemins de fer Français (SNCF) and TGV inOui.
The distance between Lyon and Istres is 248.8 km. The road distance is 388 km.
You can take a train from Lyon Part Dieu to Istres via Marseille St Charles and Miramas in around 4h 1m.