The average train between Lyon and Isernia takes 17h 1m and the fastest train takes 10h 24m. The train service runs several times per day from Lyon to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Lyon and Isernia. The earliest departure is at 9:28 AM in the morning, and the last departure from Lyon is at 5:23 PM which arrives into Isernia at 3:23 PM. All services require a transfer at Milano Centrale and take an average of 17h 1m. The schedules shown below are for the next available departures.
Want to know about travelling from Lyon to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Isernia. However, there are services departing from Lyon station and arriving at Isernia station via Milano Centrale. The journey, including transfers, takes approximately 17h 1m.
Lyon to Isernia train services, operated by Trenitalia, depart from Lyon Part Dieu station.
Lyon to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Lyon to Isernia train tickets online with Trenitalia and ItaloTreno.
The distance between Lyon and Isernia is 884.1 km. The road distance is 1,211 km.
You can take a train from Lyon Part Dieu to Isernia via Milano Centrale and Roma Termini in around 11h 11m.
