The average train between Lyon and Antwerp takes 4h 53m and the fastest train takes 4h 36m. The train service runs several times per day from Lyon to Antwerp. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lyon and Antwerp. The earliest departure is at 5:50 AM in the morning, and the last departure from Lyon is at 7:00 PM which arrives into Antwerp at 11:42 PM. All services require a transfer, and take on average 4h 53m. The schedules shown below are for the next available departures.

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4h 36m • 1 changeWant to know about travelling from Lyon to Antwerp? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Antwerp. However, there are services departing from Lyon Part Dieu station and arriving at Anvers-Central station via Brussel-Zuid / Bruxelles-Midi station. The journey, including transfers, takes approximately 4h 53m.
Lyon to Antwerp train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to Antwerp train services, operated by Belgian Railways (NMBS/SNCB), arrive at Anvers-Central station.
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The distance between Lyon and Antwerp is 609.3 km. The road distance is 703 km.
You can take a train from Lyon Part Dieu to Anvers-Central via Bruxelles-Midi in around 4h 41m.