The average train between Lyon and Agen takes 8h 8m and the fastest train takes 5h 41m. The train service runs several times per day from Lyon to Agen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Lyon and Agen. The earliest departure is at 6:40 AM in the morning, and the last departure from Lyon is at 6:10 PM which arrives into Agen at 7:19 AM. All services require a transfer, and take on average 8h 8m. The schedules shown below are for the next available departures.

5h 53m • 1 change

5h 56m • 1 change
Arrives next day

13h 9m • 1 change

5h 53m • 1 change

5h 56m • 1 change
Arrives next day

13h 13m • 1 change

5h 53m • 1 change

5h 41m • 1 change
Arrives next day

13h 9m • 1 change

5h 53m • 1 change

5h 41m • 1 change
Arrives next day

15h 4m • 1 change

5h 53m • 1 change

5h 41m • 1 change
Arrives next day

13h 9m • 1 change
Want to know about travelling from Lyon to Agen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lyon to Agen. However, there are services departing from Lyon station and arriving at Agen station via Toulouse Matabiau. The journey, including transfers, takes approximately 8h 8m.
Lyon to Agen train services, operated by TGV inOui, depart from Lyon Part Dieu station.
Lyon to Agen train services, operated by TGV inOui, arrive at Agen station.
Book your Lyon to Agen train tickets online with TGV inOui and Société Nationale des Chemins de fer Français (SNCF).
The distance between Lyon and Agen is 374.2 km. The road distance is 682 km.
You can take a train from Lyon Part Dieu to Agen via Toulouse Matabiau in around 6h 21m.