The average train between Luton and Holyhead takes 4h 27m and the fastest train takes 4h 22m. The train service runs several times per day from Luton to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Luton and Holyhead. The earliest departure is at 7:26 AM in the morning, and the last departure from Luton is at 7:24 PM which arrives into Holyhead at 11:53 PM. All services require a transfer at London St Pancras Intl and take an average of 4h 27m. The schedules shown below are for the next available departures.

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Want to know about travelling from Luton to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luton to Holyhead. However, there are services departing from Luton station and arriving at Holyhead station via London St Pancras Intl. The journey, including transfers, takes approximately 4h 27m.
Luton to Holyhead train services, operated by East Midlands Railways, depart from Luton station.
Luton to Holyhead train services, operated by East Midlands Railways, arrive at Holyhead station.
Book your Luton to Holyhead train tickets online with East Midlands Railways and Avanti West Coast.
The distance between Luton and Holyhead is 326.1 km. The road distance is 471 km.
You can take a train from Luton to Holyhead via London St Pancras Intl and London Euston in around 5h 38m.