The average train between Luthern and Mainz takes 5h 33m and the fastest train takes 4h 53m. There is a train service every few hours from Luthern to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Luthern and Mainz. The earliest departure is at 4:54 AM at night, and the last departure from Luthern is at 11:54 PM which arrives into Mainz at 8:27 AM. All services require a transfer at Basel SBB and take an average of 5h 33m. The schedules shown below are for the next available departures.


5h 8m • 2 changes


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4h 53m • 2 changes


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5h 32m • 2 changes


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5h 8m • 2 changes


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5h 32m • 2 changes


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5h 8m • 2 changes
Want to know about travelling from Luthern to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Luthern to Mainz. However, there are services departing from Luthern station and arriving at Mainz station via Basel SBB. The journey, including transfers, takes approximately 5h 33m.
Luthern to Mainz train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Luzern station.
Luthern to Mainz train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Mainz, Römisches Theater station.
Book your Luthern to Mainz train tickets online with Swiss Federal Railways (SBB CFF FFS), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Luthern and Mainz is 326.2 km. The road distance is 414 km.
You can take a train from Luzern to Mainz, Römisches Theater via Basel SBB and Mannheim, Hauptbahnhof in around 5h 19m.