The average train between Lewes and Manchester takes 3h 59m and the fastest train takes 3h 34m. There is an hourly train service from Lewes to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Lewes and Manchester. The earliest departure is at 5:11 AM in the morning, and the last departure from Lewes is at 10:45 PM which arrives into Manchester at 8:25 AM. All services require a transfer at London Victoria and take an average of 3h 59m. The schedules shown below are for the next available departures.


3h 49m • 2 changes


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3h 39m • 2 changes


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3h 40m • 2 changes


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3h 49m • 2 changes
Want to know about travelling from Lewes to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lewes to Manchester. However, there are services departing from Lewes station and arriving at Manchester station via London Victoria. The journey, including transfers, takes approximately 3h 59m.
Lewes to Manchester train services, operated by Southern, depart from Lewes station.
Lewes to Manchester train services, operated by Southern, arrive at Manchester Piccadilly station.
Book your Lewes to Manchester train tickets online with Southern, London Underground (Tube) and Avanti West Coast.
The distance between Lewes and Manchester is 327.8 km. The road distance is 378 km.
You can take a train from Lewes to Manchester Piccadilly via London Victoria, Victoria station, Euston station, and London Euston in around 3h 48m.