The average train between Lecce and Cassino takes 7h 32m and the fastest train takes 6h 4m. The train service runs several times per day from Lecce to Cassino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Lecce and Cassino. The earliest departure is at 6:07 AM in the morning, and the last departure from Lecce is at 5:07 PM which arrives into Cassino at 5:30 AM. All services require a transfer, and take on average 7h 32m. The schedules shown below are for the next available departures.

6h 39m • 1 change

6h 31m • 1 change
Arrives next day

12h 23m • 1 change

6h 4m • 1 change

6h 56m • 1 change

6h 39m • 1 change

6h 31m • 1 change

6h 56m • 1 change

7h 21m • 1 change

6h 39m • 1 change

7h 15m • 1 change

6h 4m • 1 change

6h 40m • 1 change

6h 43m • 1 change

8h 5m • 1 change
Want to know about travelling from Lecce to Cassino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lecce to Cassino. However, there are services departing from Lecce station and arriving at Cassino station via Caserta. The journey, including transfers, takes approximately 7h 32m.
Lecce to Cassino train services, operated by Trenitalia Frecce, depart from Lecce station.
Lecce to Cassino train services, operated by Trenitalia Frecce, arrive at Cassino station.
Book your Lecce to Cassino train tickets online with Trenitalia Frecce, Trenitalia and Trenitalia Intercity.
The distance between Lecce and Cassino is 386 km. The road distance is 507 km.
You can take a train from Lecce to Cassino via Caserta in around 6h 16m.