Duration 12h 6m
Distance 523.2 km
Average price 4 517 Kč
Frequency 3/day

Trip overview

The average train between Karlsruhe and Prague takes 12h 6m and the fastest train takes 9h 36m. The train service runs several times per day from Karlsruhe to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.


  1. Karlsruhe Hbf
  2. Frankfurt(Main)Hbf
  3. Dresden Hbf
  4. Prague
9h 50m
Bookable on Rome2rio
3 401 Kč - 6 673 Kč

Karlsruhe to Prague train times

Trains run three times a day between Karlsruhe and Prague. The earliest departure is at 08:00 in the morning, and the last departure from Karlsruhe is at 18:00 which arrives into Prague at 11:36. All services require a transfer, and take on average 12h 6m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Karlsruhe to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport?, What is the quickest option?, How much do tickets usually cost? and many more.

There is widespread community transmission globally.
Some travel restrictions are being lifted in Czechia. For the latest travel status, please check the official page for Czechia.

Learn More.

No, there is no direct train from Karlsruhe to Prague. However, there are services departing from Karlsruhe Hbf and arriving at Praha Hlavni Nadrazi via Frankfurt(Main)Hbf and Dresden Hbf. The journey, including transfers, takes approximately 9h 50m.

More details

The distance between Karlsruhe and Prague is 450 km. The road distance is 523.2 km.

Get driving directions

Karlsruhe to Prague train services, operated by Deutsche Bahn Intercity-Express, depart from Karlsruhe Hbf station.

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Karlsruhe to Prague train services, operated by Deutsche Bahn Eurocity, arrive at Praha Hlavni Nadrazi station.

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Book your Karlsruhe to Prague train tickets online with Omio, Omio and Omio.

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There are 3163+ hotels available in Prague. Prices start at 2 250 Kč per night.

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