The average train between Karlsruhe and Neuss takes 2h 56m and the fastest train takes 2h 55m. The train service runs several times per day from Karlsruhe to Neuss. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Karlsruhe and Neuss. The earliest departure is at 6:59 AM in the morning, and the last departure from Karlsruhe is at 8:59 PM which arrives into Neuss at 12:05 AM. All services require a transfer at Düsseldorf Hbf and take an average of 2h 56m. The schedules shown below are for the next available departures.

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 55m • 1 change
Want to know about travelling from Karlsruhe to Neuss? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Neuss. However, there are services departing from Karlsruhe station and arriving at Neuss station via Düsseldorf Hbf. The journey, including transfers, takes approximately 2h 56m.
Karlsruhe to Neuss train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Neuss train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Düsseldorf Hbf station.
Book your Karlsruhe to Neuss train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and VIAS Rail GmbH.
The distance between Karlsruhe and Neuss is 272.5 km. The road distance is 350 km.
Deutsche Bahn Intercity (DB IC) operates a train from Karlsruhe Hauptbahnhof to Düsseldorf Hbf every 4 hours. Tickets cost €60–150 and the journey takes 2h 33m.