The average train between Karlsruhe and Neuss takes 3h 22m and the fastest train takes 2h 29m. There is a train service every few hours from Karlsruhe to Neuss. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Karlsruhe and Neuss. The earliest departure is at 12:28 AM at night, and the last departure from Karlsruhe is at 9:59 PM which arrives into Neuss at 1:33 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 3h 22m. The schedules shown below are for the next available departures.


3h 7m • 2 changes

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2h 29m • 2 changesArrives next day


3h 7m • 2 changes

6h 38m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

6h 38m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

6h 38m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changes

3h 7m • 2 changesWant to know about travelling from Karlsruhe to Neuss? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Karlsruhe to Neuss. However, there are services departing from Karlsruhe station and arriving at Neuss station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 3h 22m.
Karlsruhe to Neuss train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
Karlsruhe to Neuss train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Köln Hbf station.
Book your Karlsruhe to Neuss train tickets online with Deutsche Bahn Intercity (DB IC), National Express and Deutsche Bahn Regio (DB Regional).
The distance between Karlsruhe and Neuss is 272.5 km. The road distance is 336 km.
You can take a train from Karlsruhe Hauptbahnhof to Neuss Hbf via Mannheim, Hauptbahnhof and Koeln Hbf in around 3h 1m.