The average train between Jesi and Milan takes 5h 5m and the fastest train takes 3h 45m. The train service runs several times per day from Jesi to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Jesi and Milan. The earliest departure is at 12:29 AM at night, and the last departure from Jesi is at 7:40 PM which arrives into Milan at 11:25 PM. All services require a transfer, and take on average 5h 5m. The schedules shown below are for the next available departures.

4h 3m • 1 change

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4h 34m • 1 change

4h 10m • 1 change

5h 44m • 1 change

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4h 28m • 1 change

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4h 9m • 1 change
Want to know about travelling from Jesi to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Jesi to Milan. However, there are services departing from Jesi station and arriving at Milan station via Milano Centrale. The journey, including transfers, takes approximately 5h 5m.
Jesi to Milan train services, operated by Trenitalia, depart from Ancona station.
Jesi to Milan train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Jesi to Milan train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Jesi and Milan is 387.3 km. The road distance is 443 km.
Trenitalia Frecce operates a train from Ancona to Milano Centrale hourly. Tickets cost €60–120 and the journey takes 3h 45m. Trenitalia Intercity also services this route every 2 hours.