The average train between Italy and Enschede takes 23h 43m and the fastest train takes 22h 17m. There is at least one train per day from Italy to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Italy and Enschede. The earliest departure is at 2:10 PM in the afternoon, and the last departure from Italy is at 8:05 PM which arrives into Enschede at 8:27 PM. All services require a transfer at Milano Centrale and take an average of 23h 43m. The schedules shown below are for the next available departures.
Arrives next day



26h 17m • 3 changes
Arrives next day



24h 22m • 3 changes
Arrives next day



22h 17m • 3 changes
Arrives next day



24h 22m • 3 changes
Arrives next day



22h 17m • 3 changes
Arrives next day



24h 22m • 3 changes
Want to know about travelling from Italy to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Italy to Enschede. However, there are services departing from Italy station and arriving at Enschede station via Milano Centrale. The journey, including transfers, takes approximately 23h 43m.
Italy to Enschede train services, operated by ItaloTreno, depart from Roma Termini station.
Italy to Enschede train services, operated by ItaloTreno, arrive at Enschede station.
Book your Italy to Enschede train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Italy and Enschede is 1,149.6 km. The road distance is 1,663 km.
You can take a train from Roma Termini to Enschede via Milano Centrale, Basel SBB, and Münster Hauptbahnhof in around 17h.