The average train between Isernia and Luthern takes 13h 13m and the fastest train takes 9h 41m. The train service runs several times per day from Isernia to Luthern. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Isernia and Luthern. The earliest departure is at 6:40 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Luthern at 1:41 PM. All services require a transfer at Roma Termini and take an average of 13h 13m. The schedules shown below are for the next available departures.



9h 41m • 3 changes



9h 43m • 3 changes
Arrives next day



19h 18m • 3 changes
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17h 6m • 3 changes



9h 41m • 3 changes



9h 43m • 3 changes
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19h 18m • 3 changes



9h 43m • 3 changes
Arrives next day



19h 18m • 3 changes
Arrives next day



17h 6m • 3 changes



9h 41m • 3 changes



9h 43m • 3 changes
Arrives next day



19h 18m • 3 changes
Arrives next day



17h 6m • 3 changes



9h 41m • 3 changes



9h 43m • 3 changes
Arrives next day



16h 54m • 3 changes
Want to know about travelling from Isernia to Luthern? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Luthern. However, there are services departing from Isernia station and arriving at Luthern station via Roma Termini. The journey, including transfers, takes approximately 13h 13m.
Isernia to Luthern train services, operated by Trenitalia, depart from Isernia station.
Isernia to Luthern train services, operated by Trenitalia, arrive at Arth-Goldau station.
Book your Isernia to Luthern train tickets online with Trenitalia, ItaloTreno and 3 other operators.
The distance between Isernia and Luthern is 767.8 km. The road distance is 999 km.
You can take a train from Isernia to Luzern via Roma Termini, Milano Centrale, and Arth-Goldau in around 9h 57m.