The average train between Iseo and Manchester takes 24h 54m and the fastest train takes 23h 48m. There is at least one train per day from Iseo to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Iseo and Manchester. The earliest departure is at 1:31 PM in the afternoon, and the last departure from Iseo is at 8:31 PM which arrives into Manchester at 9:19 PM. All services require a transfer at Brescia and take an average of 24h 54m. The schedules shown below are for the next available departures.
Arrives next day





22h 48m • 5 changes
Arrives next day





24h 48m • 5 changes
Arrives next day





22h 48m • 5 changes
Arrives next day





24h 48m • 5 changes
Want to know about travelling from Iseo to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Iseo to Manchester. However, there are services departing from Iseo station and arriving at Manchester station via Milano Centrale. The journey, including transfers, takes approximately 24h 54m.
Iseo to Manchester train services, operated by Trenord, depart from Brescia station.
Iseo to Manchester train services, operated by Trenord, arrive at Manchester Piccadilly station.
Book your Iseo to Manchester train tickets online with Trenord, Trenitalia Frecce and 4 other operators.
The distance between Iseo and Manchester is 1,238.4 km. The road distance is 1,757 km.
You can take a train from Iseo to Manchester Piccadilly via Brescia, Milano Centrale, Lyon Part Dieu, Lille Europe, London St Pancras Intl, and London Euston in around 16h 20m.