The average train between Iselle and Milan takes 2h 53m and the fastest train takes 2h 16m. The train service runs several times per day from Iselle to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Iselle and Milan. The earliest departure is at 5:34 AM in the morning, and the last departure from Iselle is at 7:34 PM which arrives into Milan at 9:50 PM. All services require a transfer, and take on average 2h 53m. The schedules shown below are for the next available departures.

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Want to know about travelling from Iselle to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Iselle to Milan. However, there are services departing from Iselle station and arriving at Milan station via Milano Centrale. The journey, including transfers, takes approximately 2h 53m.
Iselle to Milan train services, operated by BLS AG, depart from Domodossola station.
Iselle to Milan train services, operated by BLS AG, arrive at Milano Centrale station.
The distance between Iselle and Milan is 112.9 km. The road distance is 137 km.
Trenitalia EuroCity operates a train from Domodossola to Milano Centrale every 4 hours. Tickets cost €30–75 and the journey takes 1h 33m.