The average train between Holyhead and Ruislip takes 4h 37m and the fastest train takes 4h 32m. The train service runs several times per day from Holyhead to Ruislip. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Holyhead and Ruislip. The earliest departure is at 4:45 AM at night, and the last departure from Holyhead is at 2:48 PM which arrives into Ruislip at 7:25 PM. All services require a transfer at London Euston and take an average of 4h 37m. The schedules shown below are for the next available departures.

4h 36m • 1 change

4h 37m • 1 change

4h 32m • 1 change

4h 46m • 1 change

4h 36m • 1 change

4h 37m • 1 change

4h 32m • 1 change

4h 46m • 1 change

4h 36m • 1 change

4h 37m • 1 change

4h 32m • 1 change

4h 46m • 1 change

4h 36m • 1 change

4h 37m • 1 change

4h 32m • 1 change

4h 46m • 1 change

4h 33m • 1 change

4h 39m • 1 change

4h 37m • 1 change

4h 32m • 1 change
Want to know about travelling from Holyhead to Ruislip? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Ruislip. However, there are services departing from Holyhead station and arriving at Ruislip station via London Euston. The journey, including transfers, takes approximately 4h 37m.
Holyhead to Ruislip train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to Ruislip train services, operated by Avanti West Coast, arrive at London Euston station.
The distance between Holyhead and Ruislip is 344.5 km. The road distance is 446 km.
Avanti West Coast operates a train from Holyhead to London Euston 5 times a day. Tickets cost £90–160 and the journey takes 3h 48m.