The average train between Holyhead and Derby takes 4h 43m and the fastest train takes 3h 27m. The train service runs several times per day from Holyhead to Derby. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Holyhead and Derby. The earliest departure is at 4:45 AM at night, and the last departure from Holyhead is at 8:32 PM which arrives into Derby at 7:40 AM. All services require a transfer, and take on average 4h 43m. The schedules shown below are for the next available departures.

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Want to know about travelling from Holyhead to Derby? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Derby. However, there are services departing from Holyhead station and arriving at Derby station via Crewe. The journey, including transfers, takes approximately 4h 43m.
Holyhead to Derby train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to Derby train services, operated by Avanti West Coast, arrive at Derby station.
Book your Holyhead to Derby train tickets online with Avanti West Coast, East Midlands Railways and Transport for Wales.
The distance between Holyhead and Derby is 215 km. The road distance is 250 km.
You can take a train from Holyhead to Derby via Crewe in around 4h 6m.