The average train between Holyhead and Brussels takes 6h 22m and the fastest train takes 6h 13m. The train service runs several times per day from Holyhead to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Holyhead and Brussels. The earliest departure is at 4:45 AM at night, and the last departure from Holyhead is at 2:48 PM which arrives into Brussels at 10:35 PM. All services require a transfer at London Euston and take an average of 6h 22m. The schedules shown below are for the next available departures.

7h 20m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 19m • 1 change

7h 18m • 1 change

7h 47m • 1 change

7h 20m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 17m • 1 change

7h 20m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 17m • 1 change

7h 20m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 17m • 1 change

7h 20m • 1 change

7h 17m • 1 change

7h 13m • 1 change

7h 17m • 1 change
Want to know about travelling from Holyhead to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Holyhead to Brussels. However, there are services departing from Holyhead station and arriving at Brussels station via London Euston. The journey, including transfers, takes approximately 6h 22m.
Holyhead to Brussels train services, operated by Avanti West Coast, depart from Holyhead station.
Holyhead to Brussels train services, operated by Avanti West Coast, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Holyhead to Brussels train tickets online with Avanti West Coast and Eurostar.
The distance between Holyhead and Brussels is 671.4 km. The road distance is 794 km.
You can take a train from Holyhead to Brussel-Zuid / Bruxelles-Midi via London Euston and London St Pancras Intl in around 6h 59m.