The average train between High Wycombe and Manchester takes 4h 2m and the fastest train takes 3h 24m. There is a train service every few hours from High Wycombe to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between High Wycombe and Manchester. The earliest departure is at 12:36 AM at night, and the last departure from High Wycombe is at 8:31 PM which arrives into Manchester at 12:13 AM. All services require a transfer, and take on average 4h 2m. The schedules shown below are for the next available departures.

3h 24m • 1 change

3h 24m • 1 change

3h 24m • 1 change

3h 24m • 1 change

8h 52m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 24m • 1 change

8h 52m • 1 change

3h 31m • 1 change

3h 57m • 1 change

3h 24m • 1 change

8h 52m • 1 change

4h 16m • 1 change

4h 1m • 1 change

4h 1m • 1 change
Want to know about travelling from High Wycombe to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from High Wycombe to Manchester. However, there are services departing from High Wycombe station and arriving at Manchester station via Banbury. The journey, including transfers, takes approximately 4h 2m.
High Wycombe to Manchester train services, operated by Chiltern Railways, depart from High Wycombe station.
High Wycombe to Manchester train services, operated by Chiltern Railways, arrive at Manchester Piccadilly station.
Book your High Wycombe to Manchester train tickets online with Chiltern Railways and Cross Country.
The distance between High Wycombe and Manchester is 229.2 km. The road distance is 274 km.
You can take a train from High Wycombe to Manchester Piccadilly via Banbury in around 3h 58m.