The average train between Heppenheim and Prague takes 11h 9m and the fastest train takes 9h 25m. The train service runs several times per day from Heppenheim to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Heppenheim and Prague. The earliest departure is at 2:59 AM at night, and the last departure from Heppenheim is at 11:59 PM which arrives into Prague at 12:21 PM. All services require a transfer at Frankfurt and take an average of 11h 9m. The schedules shown below are for the next available departures.



10h 20m • 3 changes


9h 25m • 3 changes


9h 25m • 3 changes


9h 26m • 3 changes


10h 20m • 3 changes


9h 25m • 3 changes


9h 25m • 3 changes


9h 26m • 3 changes


10h 20m • 3 changes


9h 25m • 3 changes


9h 25m • 3 changes


9h 26m • 3 changes


11h 22m • 3 changes


10h 20m • 3 changes


9h 25m • 3 changes


9h 25m • 3 changes


11h 22m • 3 changes


10h 20m • 3 changes


9h 25m • 3 changes


9h 25m • 3 changesWant to know about travelling from Heppenheim to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Heppenheim to Prague. However, there are services departing from Heppenheim, Bahnhof station and arriving at Praha Hlavni Nadrazi station via Frankfurt station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 11h 9m.
Heppenheim to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Heppenheim, Bahnhof station.
Heppenheim to Prague train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
Book your Heppenheim to Prague train tickets online with Omio.
The distance between Heppenheim and Prague is 417.8 km. The road distance is 528 km.
You can take a train from Heppenheim, Bahnhof to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 6m.