The average train between Harpenden and Holyhead takes 4h 29m and the fastest train takes 4h 20m. The train service runs several times per day from Harpenden to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Harpenden and Holyhead. The earliest departure is at 7:28 AM in the morning, and the last departure from Harpenden is at 7:22 PM which arrives into Holyhead at 11:51 PM. All services require a transfer at London St Pancras Intl and take an average of 4h 29m. The schedules shown below are for the next available departures.

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Want to know about travelling from Harpenden to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Harpenden to Holyhead. However, there are services departing from Harpenden station and arriving at Holyhead station via Holyhead. The journey, including transfers, takes approximately 4h 29m.
Harpenden to Holyhead train services, operated by Thameslink, depart from London Euston station.
Harpenden to Holyhead train services, operated by Thameslink, arrive at Holyhead station.
Book your Harpenden to Holyhead train tickets online with Thameslink and Avanti West Coast.
The distance between Harpenden and Holyhead is 333.3 km. The road distance is 462 km.
Avanti West Coast operates a train from London Euston to Holyhead 5 times a day. Tickets cost £90–160 and the journey takes 3h 52m.