The average train between Genoa and Nyon takes 7h 29m and the fastest train takes 6h 58m. The train service runs several times per day from Genoa to Nyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Genoa and Nyon. The earliest departure is at 5:36 AM in the morning, and the last departure from Genoa is at 4:08 PM which arrives into Nyon at 12:13 AM. All services require a transfer at Milano Centrale and take an average of 7h 29m. The schedules shown below are for the next available departures.


6h 58m • 2 changes

7h 24m • 2 changesArrives next day


8h 5m • 2 changes

6h 58m • 2 changes

7h 24m • 2 changesArrives next day


8h 5m • 2 changesWant to know about travelling from Genoa to Nyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Genoa to Nyon. However, there are services departing from Genoa station and arriving at Nyon station via Milano Centrale. The journey, including transfers, takes approximately 7h 29m.
Genoa to Nyon train services, operated by Trenitalia, depart from Genova Brignole station.
Genoa to Nyon train services, operated by Trenitalia, arrive at Lausanne station.
Book your Genoa to Nyon train tickets online with Trenitalia, Trenitalia EuroCity and 2 other operators.
The distance between Genoa and Nyon is 304.9 km. The road distance is 483 km.
You can take a train from Genova Brignole to Nyon via Milano Centrale and Lausanne in around 7h 10m.