The average train between Euston Square and Slough takes 38 min and the fastest train takes 25 min. The train runs at least 3 times per hour from Euston Square to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 20 minutes between Euston Square and Slough. The earliest departure is at 12:34 AM at night, and the last departure from Euston Square is at 7:52 PM which arrives into Slough at 8:23 PM. All services require a transfer at Paddington and take an average of 38 min. The schedules shown below are for the next available departures.

46 min • 1 change

1h 25m • 1 change

43 min • 1 change

31 min • 1 change
Want to know about travelling from Euston Square to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Euston Square to Slough. However, there are services departing from Euston Square station and arriving at Slough station via Paddington. The journey, including transfers, takes approximately 38 min.
Euston Square to Slough train services, operated by London Underground (Tube), depart from Euston Square station.
Euston Square to Slough train services, operated by London Underground (Tube), arrive at Slough station.
Book your Euston Square to Slough train tickets online with London Underground (Tube), Great Western Railway (GWR) and Elizabeth Line (TfL).
The distance between Euston Square and Slough is 31.9 km. The road distance is 33 km.
Elizabeth Line (TfL) operates a train from Farringdon Without to Slough every 20 minutes. Tickets cost £15–30 and the journey takes 39 min.