The average train between Essen and Wetzlar takes 3h 36m and the fastest train takes 3h 8m. The train service runs several times per day from Essen to Wetzlar. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Essen and Wetzlar. The earliest departure is at 12:07 AM at night, and the last departure from Essen is at 4:34 PM which arrives into Wetzlar at 7:42 PM. All services require a transfer, and take on average 3h 36m. The schedules shown below are for the next available departures.

7h 35m • 1 change

3h 8m • 1 change

3h 8m • 1 change

3h 8m • 1 change

3h 35m • 1 change

3h 8m • 1 change

3h 8m • 1 change

3h 8m • 1 change

7h 35m • 1 change

3h 8m • 1 change

3h 8m • 1 change

3h 8m • 1 change

7h 35m • 1 change

3h 8m • 1 change

3h 8m • 1 change

3h 8m • 1 change
Want to know about travelling from Essen to Wetzlar? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Essen to Wetzlar. However, there are services departing from Essen station and arriving at Wetzlar station via Wetzlar Bahnhof. The journey, including transfers, takes approximately 3h 36m.
Essen to Wetzlar train services, operated by VIAS Rail GmbH, depart from Witten Hbf station.
Essen to Wetzlar train services, operated by VIAS Rail GmbH, arrive at Wetzlar Bahnhof station.
Book your Essen to Wetzlar train tickets online with VIAS Rail GmbH, Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Essen and Wetzlar is 144.3 km. The road distance is 203 km.
Deutsche Bahn Intercity (DB IC) operates a train from Witten Hbf to Wetzlar Bahnhof 5 times a day. Tickets cost €30–80 and the journey takes 2h 28m.