The average train between Essen and Neu-Isenburg takes 2h 59m and the fastest train takes 2h 27m. The train service runs several times per day from Essen to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Essen and Neu-Isenburg. The earliest departure is at 8:09 AM in the morning, and the last departure from Essen is at 10:09 PM which arrives into Neu-Isenburg at 4:41 AM. All services require a transfer at Koeln Hbf and take an average of 2h 59m. The schedules shown below are for the next available departures.


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Want to know about travelling from Essen to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Essen to Neu-Isenburg. However, there are services departing from Essen station and arriving at Neu-Isenburg station via Köln Hbf. The journey, including transfers, takes approximately 2h 59m.
Essen to Neu-Isenburg train services, operated by National Express, depart from Essen Hbf station.
Essen to Neu-Isenburg train services, operated by National Express, arrive at Frankfurt(Main)Hbf station.
The distance between Essen and Neu-Isenburg is 196.2 km. The road distance is 269 km.
You can take a train from Essen Hbf to Frankfurt via Koeln Hbf, Frankfurt(Main)Hbf, and Frankfurt in around 2h 50m.