The average train between Enschede and Differdange takes 9h 29m and the fastest train takes 8h 13m. The train service runs several times per day from Enschede to Differdange. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Enschede and Differdange. The earliest departure is at 5:56 AM in the morning, and the last departure from Enschede is at 9:03 PM which arrives into Differdange at 12:18 PM. All services require a transfer at Duelmen and take an average of 9h 29m. The schedules shown below are for the next available departures.





8h 15m • 5 changes





8h 13m • 5 changes





8h 13m • 5 changes





8h 43m • 5 changes





8h 22m • 5 changes





8h 22m • 5 changes





8h 15m • 5 changes





8h 15m • 5 changes





8h 22m • 5 changes





8h 22m • 5 changes





8h 15m • 5 changes





8h 15m • 5 changes





8h 22m • 5 changes





8h 22m • 5 changes





8h 15m • 5 changes





8h 15m • 5 changes





8h 22m • 5 changes





8h 22m • 5 changes





8h 15m • 5 changes





8h 15m • 5 changes
Want to know about travelling from Enschede to Differdange? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Enschede to Differdange. However, there are services departing from Enschede station and arriving at Differdange station via Duelmen. The journey, including transfers, takes approximately 9h 29m.
Enschede to Differdange train services, operated by Deutsche Bahn Regio (DB Regional), depart from Enschede station.
Enschede to Differdange train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Luxembourg, Gare Centrale station.
The distance between Enschede and Differdange is 308.1 km. The road distance is 482 km.
You can take a train from Enschede to Differdange, Gare via Duelmen, Dülmen, Bahnhof, Duisburg Hbf, Koblenz Hauptbahnhof, Trier, Hauptbahnhof, and Luxembourg, Gare Centrale in around 8h 35m.