The average train between Dortmund and Wetzlar takes 4h 10m and the fastest train takes 3h 56m. The train service runs several times per day from Dortmund to Wetzlar. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Dortmund and Wetzlar. The earliest departure is at 4:35 AM at night, and the last departure from Dortmund is at 4:36 PM which arrives into Wetzlar at 8:32 PM. All services require a transfer, and take on average 4h 10m. The schedules shown below are for the next available departures.

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4h 56m • 1 change
Want to know about travelling from Dortmund to Wetzlar? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dortmund to Wetzlar. However, there are services departing from Dortmund station and arriving at Wetzlar station via Koblenz Hauptbahnhof. The journey, including transfers, takes approximately 4h 10m.
Dortmund to Wetzlar train services, operated by Deutsche Bahn Intercity (DB IC), depart from Dortmund Hbf station.
Dortmund to Wetzlar train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Wetzlar Bahnhof station.
Book your Dortmund to Wetzlar train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Dortmund and Wetzlar is 128.6 km. The road distance is 287 km.
You can take a train from Dortmund Hbf to Wetzlar Bahnhof via Koblenz Hauptbahnhof in around 4h 45m.