The average train between Dortmund and Mosbach takes 4h 20m and the fastest train takes 4h 12m. The train service runs several times per day from Dortmund to Mosbach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Dortmund and Mosbach. The earliest departure is at 5:34 AM in the morning, and the last departure from Dortmund is at 8:36 PM which arrives into Mosbach at 1:37 AM. All services require a transfer, and take on average 4h 20m. The schedules shown below are for the next available departures.

4h 18m • 1 change

4h 13m • 1 change

4h 16m • 1 change

4h 16m • 1 change
Want to know about travelling from Dortmund to Mosbach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dortmund to Mosbach. However, there are services departing from Dortmund station and arriving at Mosbach station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 4h 20m.
Dortmund to Mosbach train services, operated by Deutsche Bahn Intercity (DB IC), depart from Dortmund Hbf station.
Dortmund to Mosbach train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mosbach, Bahnhof station.
Book your Dortmund to Mosbach train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Dortmund and Mosbach is 268.3 km. The road distance is 407 km.
You can take a train from Dortmund Hbf to Mosbach, Bahnhof via Mannheim, Hauptbahnhof in around 4h 26m.