The average train between Derby and Slough takes 2h 23m and the fastest train takes 2h 13m. The train runs at least 2 times per hour from Derby to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Derby and Slough. The earliest departure is at 4:14 AM at night, and the last departure from Derby is at 10:20 PM which arrives into Slough at 1:19 AM. All services require a transfer at London St Pancras International and take an average of 2h 23m. The schedules shown below are for the next available departures.


2h 38m • 2 changes


2h 38m • 2 changes


2h 19m • 2 changes


2h 14m • 2 changes


3h 9m • 2 changes


2h 24m • 2 changes


2h 20m • 2 changes


2h 24m • 2 changes


3h 9m • 2 changes


2h 24m • 2 changes


2h 20m • 2 changes


2h 24m • 2 changes
Want to know about travelling from Derby to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to Slough. However, there are services departing from Derby station and arriving at Slough station via London St Pancras Intl. The journey, including transfers, takes approximately 2h 23m.
Derby to Slough train services, operated by East Midlands Railways, depart from Derby station.
Derby to Slough train services, operated by East Midlands Railways, arrive at London St Pancras Intl station.
Book your Derby to Slough train tickets online with East Midlands Railways, London Underground (Tube) and 2 other operators.
The distance between Derby and Slough is 168.2 km. The road distance is 239 km.
East Midlands Railways operates a train from Derby to London St Pancras Intl hourly. Tickets cost £60–95 and the journey takes 1h 37m.