The average train between Derby and Slough takes 2h 41m and the fastest train takes 2h 21m. There is an hourly train service from Derby to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Derby and Slough. The earliest departure is at 4:14 AM at night, and the last departure from Derby is at 10:20 PM which arrives into Slough at 6:47 AM. All services require a transfer at London St Pancras Intl and take an average of 2h 41m. The schedules shown below are for the next available departures.


2h 28m • 2 changes


2h 22m • 2 changes


2h 29m • 2 changes
Arrives next day


2h 46m • 2 changes


3h 17m • 2 changes


2h 32m • 2 changes


2h 45m • 2 changes


2h 47m • 2 changes


3h • 2 changes


3h 19m • 2 changes


2h 45m • 2 changes


2h 47m • 2 changes
Want to know about travelling from Derby to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to Slough. However, there are services departing from Derby station and arriving at Slough station via London St Pancras Intl. The journey, including transfers, takes approximately 2h 41m.
Derby to Slough train services, operated by East Midlands Railways, depart from Derby station.
Derby to Slough train services, operated by East Midlands Railways, arrive at Slough station.
Book your Derby to Slough train tickets online with East Midlands Railways, Thameslink and Elizabeth Line (TfL).
The distance between Derby and Slough is 168.2 km. The road distance is 243 km.
You can take a train from Derby to Slough via London St Pancras Intl, Farringdon, and Farringdon Without in around 2h 32m.