The average train between Derby and Ayr takes 6h 52m and the fastest train takes 5h 56m. The train service runs several times per day from Derby to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Derby and Ayr. The earliest departure is at 6:24 AM in the morning, and the last departure from Derby is at 9:48 PM which arrives into Ayr at 10:24 AM. All services require a transfer at Crewe and take an average of 6h 52m. The schedules shown below are for the next available departures.


5h 57m • 2 changes
Arrives next day


5h 56m • 2 changes
Arrives next day


12h 36m • 2 changes


5h 58m • 2 changes


5h 59m • 2 changes


5h 58m • 2 changes


5h 56m • 2 changes


5h 58m • 2 changes


5h 59m • 2 changes


5h 58m • 2 changes


5h 56m • 2 changes


5h 58m • 2 changes


5h 59m • 2 changes


5h 58m • 2 changes


5h 56m • 2 changes


5h 59m • 2 changes


6h • 2 changes


5h 58m • 2 changes


5h 57m • 2 changes


6h 10m • 2 changes


6h 9m • 2 changes
Arrives next day


13h 40m • 2 changes


5h 58m • 2 changes


5h 59m • 2 changes


5h 58m • 2 changes


5h 56m • 2 changes
Want to know about travelling from Derby to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to Ayr. However, there are services departing from Derby station and arriving at Ayr station via Crewe. The journey, including transfers, takes approximately 6h 52m.
Derby to Ayr train services, operated by East Midlands Railways, depart from Derby station.
Derby to Ayr train services, operated by East Midlands Railways, arrive at Ayr station.
Book your Derby to Ayr train tickets online with East Midlands Railways, Avanti West Coast and ScotRail.
The distance between Derby and Ayr is 349.1 km. The road distance is 535 km.
You can take a train from Derby to Ayr via Crewe and Glasgow Central in around 6h 39m.