Derby to Ayr Trains

Trip Overview

The average train between Derby and Ayr takes 6h 51m and the fastest train takes 5h 56m. The train service runs several times per day from Derby to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 51m
Duration: 332 mi
Distance: £142
Average price: Every 4 hours
Frequency

Train via Crewe

best

Take the train from Derby to Crewetrain
Take the train from Crewe to Glasgow Centraltrain
Take the train from Glasgow Central to Ayrtrain

6h 40m

£118–188

Derby to Ayr train times

Trains run every 4 hours between Derby and Ayr. The earliest departure is at 6:24 AM in the morning, and the last departure from Derby is at 9:48 PM which arrives into Ayr at 10:24 AM. All services require a transfer at Crewe and take an average of 6h 51m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

2:26 PM → 8:22 PM
5h 56m • 2 changes
4:26 PM → 10:23 PM
5h 57m • 2 changes
6:26 PM → 12:22 AM
Arrives next day
5h 56m • 2 changes
9:48 PM → 10:24 AM
Arrives next day
12h 36m • 2 changes

Departing Tuesday, November 10, 2026

6:24 AM → 12:22 PM
5h 58m • 2 changes
8:24 AM → 2:23 PM
5h 59m • 2 changes
10:26 AM → 4:24 PM
5h 58m • 2 changes
12:26 PM → 6:22 PM
5h 56m • 2 changes
Show more

Departing Wednesday, November 11, 2026

6:24 AM → 12:22 PM
5h 58m • 2 changes
8:24 AM → 2:23 PM
5h 59m • 2 changes
10:26 AM → 4:24 PM
5h 58m • 2 changes
12:26 PM → 6:22 PM
5h 56m • 2 changes
Show more

Departing Thursday, November 12, 2026

6:24 AM → 12:22 PM
5h 58m • 2 changes
8:24 AM → 2:23 PM
5h 59m • 2 changes
10:26 AM → 4:24 PM
5h 58m • 2 changes
12:26 PM → 6:22 PM
5h 56m • 2 changes
Show more

Departing Friday, November 13, 2026

6:24 AM → 12:22 PM
5h 58m • 2 changes
8:24 AM → 2:23 PM
5h 59m • 2 changes
10:26 AM → 4:24 PM
5h 58m • 2 changes
12:26 PM → 6:22 PM
5h 56m • 2 changes
Show more

Departing Saturday, November 14, 2026

6:24 AM → 12:23 PM
5h 59m • 2 changes
8:23 AM → 2:23 PM
6h • 2 changes
10:26 AM → 4:24 PM
5h 58m • 2 changes
12:26 PM → 6:23 PM
5h 57m • 2 changes
Show more

Departing Sunday, November 15, 2026

2:43 PM → 8:53 PM
6h 10m • 2 changes
4:43 PM → 10:52 PM
6h 9m • 2 changes

Frequently asked questions

Want to know about travelling from Derby to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.