The average train between Debrecen and Prague takes 11h 3m and the fastest train takes 10h 19m. The train service runs several times per day from Debrecen to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Debrecen and Prague. The earliest departure is at 6:04 AM in the morning, and the last departure from Debrecen is at 9:04 PM which arrives into Prague at 12:23 PM. All services require a transfer, and take on average 11h 3m. The schedules shown below are for the next available departures.

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Want to know about travelling from Debrecen to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Debrecen to Prague. However, there are services departing from Debrecen station and arriving at Prague station via Budapest-Nyugati. The journey, including transfers, takes approximately 11h 3m.
Debrecen to Prague train services, operated by Hungarian Railways (MÁV), depart from Debrecen station.
Debrecen to Prague train services, operated by Hungarian Railways (MÁV), arrive at Praha Hlavni Nadrazi station.
The distance between Debrecen and Prague is 598.9 km. The road distance is 826 km.
You can take a train from Debrecen to Praha Hlavni Nadrazi via Budapest-Nyugati in around 10h 50m.